Season 14 of the long-running medical drama will premiere on Channel 7 with two back-to-back episodes on Tuesday January 30 at 10pm.
The new episodes will focus on Meredith (Ellen Pompeo) and the team helping Owen's (Kevin McKidd) sister after her shocking return.
Actress Abigail Spencer will replace Bridget Regan as Owen’s sister Megan Hunt.
Regan was unavailable to return due to a scheduling conflict.
With the 2018 in full swing, other shows returning to TV include The Good Doctor and My Kitchen Rules (both Monday January 29 on 7).