The actress, 55, looked to be in good spirits as she stepped out for the Farrah Fawcett Tex-Mex Fiesta for the Performing Arts in Beverly Hills.
The Melrose Place star posed for photos with the foundation's President and CEO Alana Stewart.
In March this year, Locklear took time out in Hawaii after reports surfaced claiming she had entered rehab again.
The Perfect Man actress has battled drug and alcohol abuse over the years.
In June 2008 she received treatment for anxiety and depression, and in 2010 she completed a 30-day stint in rehab.
In January 2012, Locklear was hospitalised after a call to emergency services was made her home.
Reports at the time suggested that the actress mixed alcohol with prescription medication.