The actress told Us Weekly how a scene for zombie comedy Santa Clarita Diet almost killed her.
In one episode, her character was required to jump on someone's back to kill him. However, things went awry when she fell and hit her head on concrete.
The shows's creator Victor Fresco said the actor "was a wide guy and Drew didn’t get a great grip. Then he held onto her legs as she slipped off, and so she just pivoted down all the way and just hit her head. I thought, 'That's it. We've killed Drew Barrymore.'"
Drew added: "It was f*****g terrifying. It was very serious. I've never had a feeling like that in my life."
Paramedics rushed to the scenes and she spent two days in hospital undergoing MRIs and CAT scans - thankfully she was OK.
"I love that this group of people, who aren't family necessarily, are coming together and care about my well-being," said.
"It was a nice moment where you see the good in people."
Santa Clarita Diet airs on Netflix.