"It's because I got really skinny," she explained.
Despite his desire to focus on the drama, shock jock Kyle defended his close friend and colleague, clarifying the health-conscious star would never dabble in illicit substances.
After swiftly changing the subject, Jackie felt the need to address the damaging accusation later in the broadcast, even swearing on her daughter Kitty's life that she's "never done cocaine".
"When I tell people that, they're like, 'What?! You're in the industry. How could you have not even tried it?' But I've just never been interested. I really haven't," she said, adding the rumour was started by a "few people" in her industry who were "bitchy" and desperate to start drama.
Earlier this month, Jackie also addressed her "secret romance" with Dr Chris Brown after New Idea sources claimed the showbiz duo have been privately seeing each other for months.
"Word is they've been hanging out in Bondi," the insider spilled. "[Coronavirus lockdowns] have actually been perfect timing for them, because they have months to explore things in private without the added stress of being busted out in public together."
The spy even went so far as to suggest the global pandemic had been a "blessing in disguise" for the pair because it has allowed their relationship to develop under the radar.
Despite being linked in the to the hunky TV star in the past, Jackie revealed she's single and hardly knows the veterinarian.
"No that's not true. No secret relationship with Chris Brown. I don't really know Chris Brown that well. I don't even have his number."