The star rocked up at Chinese Theater in Los Angeles to support of her friend Jason Bateman whose film Game Night was being screened.
In the photos obtained by TMZ, the former Friends star appeared to be missing her signature smile.
While Aniston, 49, did not walk the red carpet, she made her way into the event quietly.
Aniston and Bateman have been close buddies for two decades and have worked alongside each other in five films, including Horrible Bosses and The Office Christmas Party. In 2017, Aniston even gave the comedic actor an emotional tribute when he was awarded a star on the Hollywood Walk of Fame.
“The part that I’m the luckiest that I get to witness is Jason Bateman the husband, the father, the fantastic friend and, as we lovingly call him, the grandfather,” she said. “It’s like, ‘Is he young? Is he old? He looks 12, he acts 100!’ But even in his most restful state, he is one of the loveliest men to be around.”