Twisted Sisters is an Investigation Discovery show, consisting of ten hour-long episodes following stories of sisters who turned on each other.
The first episode of the 44 Blue Productions series is called "The Naked Truth," which delves into two separate homicides across Oregon that are linked to sisters.
Viewers will get an intimate look into the murderous stories, as interviews with immediate family members and friends of these "Twisted Sisters" will feature in the show.
"This series shows how strong the bonds between sisters really are but how twisted they can become when they’re triggered by jealousy," said Khloe.
It's no surprise that Koko has chosen a sister-related true-crime series to invest in, as she has been dealing with sister-drama her whole life.
The Kardashian sisters are some of the most successful people in their respective industries, with Kendall Jenner being the highest-paid model in the world and Kylie Jenner being the youngest self-made billionaire.
With rampant success comes a heavy dose of sibling rivalry, and their explosive fights have been well documented on Keeping Up With The Kardashians.
WATCH: Kylie Jenner calls Kim Kardashian out for bullying
The president of Investigation Discovery channel, Henry Schleiff, said he was "thrilled" to have Khloe's "unique perspective" on the deadly drama.
"It’s no mystery as to why Khloé’s expertise on sisterhood – and love of true crime stories – have made this such a huge hit with our audience!”
Season Two of Twisted Sisters airs on Mondays on Investigation Discovery.