The couple, who would have celebrated their 12th wedding anniversary in August, share one son, Kal-el Coppola Cage, 10.
Cage, 52, met Kim, 32, in February 2004 when she served him while working as a waitress in a Los Angeles restaurant. They were engaged two months later before tying the knot on a ranch in Northern California.
This is Cage's third marriage: He was wed to Lisa Marie Presley for almost four months in 2002 before filing for divorce, and, prior to that, to Patricia Arquette for five years.
Cage also has a 25-year-old son, Weston, from a relationship with model Christina Fulton.