The actress was taken by stretcher off of her return flight from Cancun, Mexico to Los Angeles after allegedly having an outburst on the flight, an official close to the situation confirms to WHO.
"She was met by paramedics at LAX as soon as her plane arrived," the source says. "It looks like she had taken a combination of prescription medication with alcohol. We don't know what sort of prescription medications."
The source adds that Blair was transported to a local hospital.
Witnesses who were also on the flight told TMZ that Blair, 43, was seated in first class, enjoying a glass of wine when she started to cry and talk about fears regarding an unnamed male.
"He burns my private parts. He won't let me eat or drink," she reportedly stated. "He beats me. He's going to kill me."
Afterwards, two nurses who were on the flight reportedly tended to Blair, checking her bags for pills before the pilot called ahead to report that a passenger on board was mixing medication with alcohol, TMZ reports.
A rep for Blair rep did not immediately respond to WHO's request for comment.
According to her Instagram account, American Crime Story star headed south of the border with her 4-year-old son Arthur Saint for a beachside Father's Day celebration with her ex Jason Bleick, Arthur's father.
As their plane was departing, Blair posted a picture of herself and Arthur on Instagram playing with toy planes.
"We're leaving on a jet plane. Dad is already asleep," she captioned the photo. "Not for long. Bwahahaha. #fathersdayweekend."