The couple's divorce comes only days after Aniston celebrated her 49th birthday. Notably, Theroux was not by Aniston's side as she celebrated special day Malibu, California along with girlfriends Courteney Cox, Andrea Bendewald, Leigh Kilton-Smith and Kristin Hahn on Sunday.
Meanwhile, according to PEOPLE, Theroux was spotted in New York City walking his dog.
Aniston and Theroux, 46, first met on the set of 2008’s Tropic Thunder and officially started in 2011. The pair then married in a secret ceremony on August 5, 2015.
The couple is yet to make any comments on the split.
This is a developing story.