The Vogue spread features 15 women, including Jane Fonda, Salma Hayek and New Zealand Prime Minister Jacinda Ardern.
Across the front is the header, “Forces for CHANGE," as part of Meghan's decision to showcase impactful people in the cover.
"The Duchess chose a diverse selection of women from all walks of life, each driving impact and raising the bar for equality, kindness, justice and open-mindedness," the caption read.
According to the editor, the Duchess of Sussex did not include herself in the cover, as she thought it would be "a ‘boastful’ thing to do for this particular project."
“She wanted, instead, to focus on the women she admires.”
Meghan often makes a point of avoiding upstaging any causes and people she supports.
Royal expert Richard Fitzwilliams told Express that the Duchess of Sussex wears black to avoid garnering too much attention at events.
"The dress can become the news," commented Fitzwilliams, adding, “wearing black does two things, it allows the cause that she is supporting and the people she is meeting to be more prominent."
Fitzwilliams explained that black is a “safe colour” and “tends to mean that more publicity is given to the cause and the people”.
According to the Instagram post shared on the Sussex Royal account, Meghan said, "Guest Editing the September issue of British Vogue has been rewarding, educational and inspiring," and thanked her friends for "lending their time and energy to help within these pages and on the cover."
The 15 women on the cover are Adwoa Aboah, Adut Akech, Ramla Ali, Jacinda Ardern, Sinead Burke, Gemma Chan, Laverne Cox, Jane Fonda, Salma Hayek Pinault, Jameela Jamil, Chimamanda Ngozi Adichie, Francesca Hayward, Yara Shahidi, Greta Thunberg and Christy Turlington Burns.
The spread also features "an exclusive interview between The Duchess and former First Lady of the United States Michelle Obama, a candid conversation between The Duke of Sussex and Dr Jane Goodall, inspirational articles written by Brené Brown, Jameela Jamil and many others."
The Duchess also expressed gratitude towards Edward for the "wonderful opportunity."
The 47-year-old said the feeling was mutual, saying, "to have the country’s most influential beacon of change guest edit British Vogue at this time has been an honour, a pleasure and a wonderful surprise."